Québec siblings with rare orphan disease lead to discovery of rare genetic diseases

Mutations in a gene involved in brain development have led to the discovery of two new neurodevelopmental diseases by an international team led by researchers at McGill University and CHU Sainte-Justine Research Center. The first...

Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit...

A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates

Monoclonal antibody production We previously described production of 2AC7 and 4BA7 anti-PfRH5 murine hybridomas18. mRNA isolated from the hybridomas was used as a template to RT-PCR amplify the respective antibody rearranged variable heavy and light...

NASA-NOAA satellite catches intense Tropical Cyclone Kenneth make landfall in northern Mozambique

Credit: NASA/NOAA/ University of Wisconsin – Madison, SSES-CIMSS, William Straka III Mozambique is still recovering from deadly Tropical Cyclone Idai, and a second powerful tropical cyclone has...

European Biotechnology in 2019 and Beyond: What’s Hot and What’s Not?

We spend a lot of time focusing on specific developments in biotechnology, but sometimes it’s good to take a step back and look at the bigger picture. With this in mind, I asked three...

UK Scientists Engineer Cell Membrane for Long-Lasting Cell Therapy

Scientists at the University of Bristol, UK, have made a cell therapy that produces a glue-like hydrogel, which could make stem cells last for longer in the body and help wound healing in conditions...

A New Clue in the Mystery of ALS, Frontotemporal Dementia

A special focus on rogue proteins may hold future promise in stopping the progression of nerve cell destruction in people who have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia. ALS, a rare but devastating disorder...

Teens prefer harm reduction messaging on substance use

Zero-tolerance messaging tuned out by most teenagers Credit: University of British Columbia For many parents, talking to their children about substance use is like navigating a field of...

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

1. Bronicki, L. M. et al. Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A. Eur J Hum Genet 23, 1482–1487 (2015). 2. van Bon, B. W. et al. Disruptive de...

Can Anti-Aging Research Keep Us Healthy in the Long Run?

Searching for the fountain of eternal youth has been the dream of humanity for millennia. While this is still in the realms of science fiction, anti-aging companies are hoping to tackle aging-related diseases by...

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