uniQure Stocks Up With First Phase III Results of Hemophilia B Gene Therapy

Gene therapies for the rare blood clotting disorder hemophilia B have taken a step closer to the market as Dutch developer uniQure became the first to release interim phase III results last week. Hemophilia is...

Could beta-blockers be a potential treatment for COVID-19?

Thought LeadersDr. Nirmal RobinsonDr. Vincenzo DesiderioDr. Antonio Barbieri News-Medical spoke to researchers Dr. Nirmal Robinson, Dr. Vincenzo Desiderio, and Dr. Antonio Barbieri about their latest research into beta-blockers, and how they could potentially be used...

Gene analysis may increase the effect of antidepressant and antipsychotic drugs

In a new study published in the journal JAMA Psychiatry, researchers at Karolinska Institutet have studied CYP2C19 and CYP2D6 genes impact on treatment with antidepressants and antipsychotic drugs. The study shows that control of...

Novel homozygous variant in the TPO gene associated with congenital hypothyroidism and mild-intellectual disability

Congenital hypothyroidism (CH) is diagnosed as thyroid hormone deficiency in newborn infants with an incidence of 1:2000 to 1:4000 live births worldwide1. Approximately 80–85% of CH cases are associated with thyroid dysgenesis (TD); either...

Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

Materials and reagents The phospholipids, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- (DSPE-mPEG2000), and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- (DSPE-PEG(2000)-succinyl) were purchased from Avanti Polar Lipids, Inc. (Alabaster, AL). Cholesterol (Chol), N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), and N-Hydroxysuccinimide (NHS) were purchased from Sigma-Aldrich (St. Louis,...

Irreversible hotter and drier climate over inner East Asia

Heatwaves pushing Mongolia’s climate to a tipping point Credit: Ken Shono, Unsplash Mongolia’s semi-arid plateau may soon become as barren as parts of the American Southwest due to...

AstraZeneca’s Covid-19 Vaccine Proves Its Worth in Phase III

A much anticipated Covid-19 vaccine, developed by the University of Oxford and AstraZeneca, achieved 70% efficacy in phase III interim data. While less effective on paper, it could prove cheaper and easier to distribute...

ECDC and WHO call for improved HIV testing in Europe

AIDS-free future at stake Credit: ECDC The number of people living with undiagnosed HIV is increasing in the WHO European Region. According to data published today by ECDC...

Stem cell study identifies enzyme with potential for cancer treatment

The study, published by University of Alberta biologists, identifies an inhibition mechanism of an enzyme called Myt1 kinase, which manages how stem cells develop and differentiate during organ development in fruit flies. Image credit: Jim...

ETRI Hologram Technologies won I-zone Best Prototype Award in Displayweek 2020

1μm pixel pitch panel and 360° table top hologram were exhibited. warded for the first time to South Korea, a recognition of ETRI’s future display technology Credit: Electronics and Telecommunications Research Institute(ETRI)

Recent posts

Random article