UK Scientists Engineer Cell Membrane for Long-Lasting Cell Therapy

Scientists at the University of Bristol, UK, have made a cell therapy that produces a glue-like hydrogel, which could make stem cells last for longer in the body and help wound healing in conditions...

A New Clue in the Mystery of ALS, Frontotemporal Dementia

A special focus on rogue proteins may hold future promise in stopping the progression of nerve cell destruction in people who have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia. ALS, a rare but devastating disorder...

Teens prefer harm reduction messaging on substance use

Zero-tolerance messaging tuned out by most teenagers Credit: University of British Columbia For many parents, talking to their children about substance use is like navigating a field of...

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

1. Bronicki, L. M. et al. Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A. Eur J Hum Genet 23, 1482–1487 (2015). 2. van Bon, B. W. et al. Disruptive de...

Can Anti-Aging Research Keep Us Healthy in the Long Run?

Searching for the fountain of eternal youth has been the dream of humanity for millennia. While this is still in the realms of science fiction, anti-aging companies are hoping to tackle aging-related diseases by...

Risk factors identified for patients undergoing knee replacements

In the largest study of its kind, researchers from the Musculoskeletal Research Unit at the University of Bristol have identified the most important risk factors for developing severe infection after knee replacement. Patients who...

Acupuncture can be a wonderful tool for preventing number of diseases

Well-recognized for its therapeutic effects, acupuncture is increasingly being appreciated for its ability to promote wellness and contribute to the prevention of a broad range of conditions. A new study, which demonstrates the promise...

Can we solve the riddle of the coral reef halos?

Credit: Copyright: CNES/Airbus; DigitalGlobe.  Coral reefs worldwide are threatened by a variety of human impacts. Fishing is among the most pressing threats to reefs, because it occurs...

OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances cell-state reprogramming towards epithelial lineages

Selection of MET-TF candidates in fibroblasts To identify the TFs promoting MET in fibroblasts, we first selected candidate MET-TFs among 1995 TF genes annotated by functional annotation of mammalian genome 5 (FANTOM5)21, based on a...

2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice

TCDD abolished daily oscillations in relative liver weight The effects of TCDD on body and liver weight were examined following oral gavage with sesame oil vehicle or 30 µg/kg TCDD every 4d for 28d. At euthanasia,...

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