Development and application of a high-content virion display human GPCR array

Fabrication of a non-odorant VirD-GPCR array To develop the first high-content VirD array, we decided to focus on the 370 non-odorant GPCRs. We assembled a collection of open reading frames (ORFs) encoding 337 non-odorant GPCRs...

Can we solve the riddle of the coral reef halos?

Credit: Copyright: CNES/Airbus; DigitalGlobe.  Coral reefs worldwide are threatened by a variety of human impacts. Fishing is among the most pressing threats to reefs, because it occurs...

HKUST physicist contributes to new record of quantum memory efficiency

Credit: The Hong Kong University of Science and Technology Like memories in computers, quantum memories are essential components for quantum computers – a new generation of data processors that obey quantum mechanics laws and can...

Plant Cells Eat Their Own … Membranes and Oil Droplets

Study IDs dual role for “autophagy”—a.k.a. “self-eating”—in building and breaking down plant oils. Manipulating the process could drive up oil accumulation in bioenergy crops. Changcheng Xu (rear, left), Linhui Yu, and Jilian Fan (seated) with...

Janssen and Genmab Team Up Again for Another Potential Cancer Blockbuster

Janssen and the Danish biotech Genmab will collaborate to develop a new antibody that could outperform their blockbuster cancer drug Darzalex in certain types of blood cancer. Genmab will develop the antibody treatment until it...

Can Anti-Aging Research Keep Us Healthy in the Long Run?

Searching for the fountain of eternal youth has been the dream of humanity for millennia. While this is still in the realms of science fiction, anti-aging companies are hoping to tackle aging-related diseases by...

Molecular-scale visualization and surface charge density measurement of Z-DNA in aqueous solution

1. Watson, J. D. & Crick, F. H. C. Molecular Structure of Nucleic Acids. Nature 171, 737–738 (1953). 2. Zhao, J., Bacolla, A., Wang, G. & Vasquez, K. M. Non-B DNA structure-induced genetic instability and evolution. Cell....

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

1. Giovannoni, J., Nguyen, C., Ampofo, B., Zhong, S. & Fei, Z. The epigenome and transcriptional dynamics of fruit ripening. Annu. Rev. Plant Biol. 68, 61–84 (2017). 2. Ramdath, D. D., Isaacs, R. L., Teelucksingh, S. &...

Global HER2 testing survey raises questions about priorities for breast cancer resources

ESMO Breast Cancer Congress, May 2-4, 2019, Berlin, Germany Credit: European Society for Medical Oncology Lugano, Switzerland, 30 April 2019 – A global survey of HER2 testing has...

Minicircle DNA: Can This Technology Change CAR-T Therapy For the Better?

In biotechnology, plasmids are commonly used as vectors for the replication and cloning of recombinant DNA. For decades, scientists have been using plasmids for the development of therapies, the most recent one of which...

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