2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice

TCDD abolished daily oscillations in relative liver weight The effects of TCDD on body and liver weight were examined following oral gavage with sesame oil vehicle or 30 µg/kg TCDD every 4d for 28d. At euthanasia,...

Can nanotechnology repair body organs and heal wounds? Let’s find out

Your body’s cellular structure is programmable, making it possible for it to be changed into other kinds of cells. And today, already a number of scientific studies have found at least a couple of...

Can we solve the riddle of the coral reef halos?

Credit: Copyright: CNES/Airbus; DigitalGlobe.  Coral reefs worldwide are threatened by a variety of human impacts. Fishing is among the most pressing threats to reefs, because it occurs...

Development and application of a high-content virion display human GPCR array

Fabrication of a non-odorant VirD-GPCR array To develop the first high-content VirD array, we decided to focus on the 370 non-odorant GPCRs. We assembled a collection of open reading frames (ORFs) encoding 337 non-odorant GPCRs...

HKUST physicist contributes to new record of quantum memory efficiency

Credit: The Hong Kong University of Science and Technology Like memories in computers, quantum memories are essential components for quantum computers – a new generation of data processors that obey quantum mechanics laws and can...

George Mason University breast cancer treatment patent licensed by Targeted Pharmaceuticals

George Mason University patent with applications to breast cancer treatment licensed by Targeted Pharmaceuticals, a cannabinoid-based drug discovery company Credit: Copyright: www.gmu.edu Manassas, Va. – A patent granted...

Researchers unveil experimental compound to block therapeutic target in blood cancer

Credit: UNC Lineberger CHAPEL HILL, North Carolina – Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed...

Single-cell three-dimensional genome structures of rice gametes and unicellular zygotes

1. Dekker, J., Rippe, K., Dekker, M. & Kleckner, N. Capturing chromosome conformation. Science 295, 1306–1311 (2002). 2. Lieberman-Aiden, E. et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 326, 289–293...

Janssen and Genmab Team Up Again for Another Potential Cancer Blockbuster

Janssen and the Danish biotech Genmab will collaborate to develop a new antibody that could outperform their blockbuster cancer drug Darzalex in certain types of blood cancer. Genmab will develop the antibody treatment until it...

Minicircle DNA: Can This Technology Change CAR-T Therapy For the Better?

In biotechnology, plasmids are commonly used as vectors for the replication and cloning of recombinant DNA. For decades, scientists have been using plasmids for the development of therapies, the most recent one of which...

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